A septic tank is a living system. Bacteria in the tank and soil break down waste, and they do best on a steady diet. A lake house gives them the opposite: weeks of nothing, then a holiday weekend with every bedroom full, the dishwasher running twice a day and a boat crew showering off. Georgia sizes tanks by bedrooms rather than by typical occupancy for exactly this reason, and a lake house should be designed for the crowded weekend, not the quiet month.
The other lake-specific stress is power. On Oconee and Sinclair many systems have a pump, and aerobic units run blowers. Georgia's manual warns that aerobic performance drops after outages longer than 48 to 72 hours, and Piedmont tells its grinder-pump customers to cut water use when the power is out because the pump stops and the basin can overflow. A summer storm that knocks out the lines while the house is full is when alarms go off.
Rentals deserve their own planning. Greene County only allows a short-term rental inside a Short-Term Rental Overlay District with an annual county license, and an eight-bedroom house rented every weekend in season puts far more water through a tank than an owner's family ever will. If you plan to rent, tell the designer the real bedroom count and the real use.